Sangui Biotech: Series of preclinical trials concluded successfully

Witten, Germany, March 18, 2015 - The research team embracing SanguiBioTech GmbH, the Excellence Cluster Cardio Pulmonary System (ECCPS) and TransMIT Gesellschaft für Technologietransfer mbH has now successfully concluded a series of preclinical trials at Giessen University dedicated to the indication of septic shock. The interim results which were communicated in November 2014 were now confirmed on a statistically significant basis. The hemoglobin based product SBT102 developed by SanguiBioTech does improve the oxygen supply of vital organs. The research team under the direction of professors Ralph T. Schermuly and Ardeshir Ghofrani comes to the conclusion: "The intraperitoneal application of SBT102 is an innovative and effective therapy to avoid tissue hypoxemia. The restoration of intestinal oxygenation will have an impact on tissue integrity and eventually on patient survival." A comprehensive scientific report is currently being elaborated.

Severe sepsis and septic shock are among the most common causes of death in intensive care. Studies in Germany showed that sepsis had a prevalence of 11% in German intensive care units and a 90-day mortality of 54%. Direct cost associated with treating these patients amount to around EUR1.77 bn., representing 30% of the intensive care budget. Indirect cost are being estimated to reach around EUR4.5 bn. It is to be assumed, therefore, that the total cost relating to severe sepsis and septic shock for the German health system amount to approx. EUR6.3 bn. per year.

Sangui BioTech International, Inc. ("SGBI") is a holding company the shares of which are being traded on the OTCQB venture stage marketplace for early stage and developing U.S. and international companies (OTCQB: SGBI). Companies are current in their reporting and undergo an annual verification and management certification process. Sangui shares also trade on the OTC markets of Berlin and Hamburg-Hannover stock exchanges (symbol: SBH). Its purpose is to provide financing and access to the capital markets for the enterprises of the Sangui group. SanguiBioTech GmbH is a ninety percent subsidiary of Sangui BioTech International, Inc.

ECCPS is an organization set up jointly by the universities of Frankfurt and Giessen together with the Max Planck Institute for Heart and Lung Research in Bad Nauheim. It ranks among the world's leading organizations of this type. This unique centre for translational medicine combines innovative medical research in the field of heart and lung diseases with their practical advancements based on preclinical and clinical studies. Its aim is to work together with industry on developing innovative drugs and substances.

TransMIT Gesellschaft für Technologietransfer mbH (www.transmit.de) being the unit in charge of technology transfer at Justus-Liebig University in Giessen is involved in carrying out this project.

For more information please contact:

Joachim Fleing
Phone: +49 (179) 7963472
Fax: +49 (2302) 915191
e-mail: fleing@sangui.de